09-05-2020, 11:13 AM
How did the Coronavirus get HIV proteins?
This is not a scientific post in any way. Do not take away any wrong conclusions please! People should know though that virologists are a bit puzzeled atm about how this virus got these structural features.
SARS-CoV-2 virus that causes COVID-19 has some interesting properties. On its outside mantle are proteins that are usually found on the HIVirus that causes AIDS. Both viruses come from completely different families but use a spike protein to get inside human cells (kind of like a key to a lock). The thing that scientists think can not be by chance is that this virus has proteins on it's wall, which are almost structurally identical to HIV. "The evolution of 2019-nCoV remains elusive" [1]
Coronaviridae (Family of the current Coronavirus)
- RNA virus
- enveloped
- viral RNA used by cells own machinery to make more virus
Retroviridae (Family of HIV)
- RNA virus
- enveloped
- viral RNA (once inside the cell) is converted to DNA and then inserted into cells own DNA, to make building blocks for more virus
![[Image: SARS-CoV-2_without_background.png]](https://upload.wikimedia.org/wikipedia/commons/8/82/SARS-CoV-2_without_background.png)
For more information see the article below:
"Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag"
1. doi.org/10.1101/2020.01.30.927871
This is not a scientific post in any way. Do not take away any wrong conclusions please! People should know though that virologists are a bit puzzeled atm about how this virus got these structural features.
SARS-CoV-2 virus that causes COVID-19 has some interesting properties. On its outside mantle are proteins that are usually found on the HIVirus that causes AIDS. Both viruses come from completely different families but use a spike protein to get inside human cells (kind of like a key to a lock). The thing that scientists think can not be by chance is that this virus has proteins on it's wall, which are almost structurally identical to HIV. "The evolution of 2019-nCoV remains elusive" [1]
Coronaviridae (Family of the current Coronavirus)
- RNA virus
- enveloped
- viral RNA used by cells own machinery to make more virus
Retroviridae (Family of HIV)
- RNA virus
- enveloped
- viral RNA (once inside the cell) is converted to DNA and then inserted into cells own DNA, to make building blocks for more virus
![[Image: SARS-CoV-2_without_background.png]](https://upload.wikimedia.org/wikipedia/commons/8/82/SARS-CoV-2_without_background.png)
For more information see the article below:
"Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag"
1. doi.org/10.1101/2020.01.30.927871