I guess you'd have to define your genres
Most of the breakout games have some genius twist that makes them push their envelope.
I agree FPS all follow in the same pattern, that's partly because we haven't figured out other useful POV action
I liked MYTH, with its environmental effects, but it didn't spawn many imitators.
Witcher's only bad choices was interesting, but does it redefine a genre?
Let's construct a framework or a Venn diagram.