For web development you didn't specify so I'll assume full stack.
Learning HTML/CSS/JS is going to get you very far with a lot of different technologies. I currently use both Angular and React for different projects, and both seem very versatile for front-end capabilities.
I also have used many different backend technologies. Node.js, .Net Core, asp.net, all with their pros and cons. I would honestly just pick one from the "top 5 list" and go for it, there is usually a lot of overlap between these frameworks and learning one will benefit you in learning others as well.